VxP Pharma offers a complete range of drug metabolism and pharmacokinetic (DMPK) studies in support of multiple programs, from drug candidate selection to regulatory submission. Our experienced ADME and bioanalytical scientists can design and interpret any in-vitro/in-vivo components of your drug metabolism studies based on the program goals. Our laboratories offer fully validated and networked management systems for multiple study types, including radioisotopic, chromatographic, and pharmacokinetic evaluations.
VxP Pharma offers custom designed ADME studies in multiple species of lab animals, using cold or radiolabeled test materials with multiple administration routes to choose from. Our experienced scientists, including toxicologists, pathologists, veterinary surgeons, bioanalytical chemists, and regulatory specialists have designed and performed multiple ADME studies with a variety of different animal models and have routinely perform mass balance and tissue distribution studies to determine tissue half-life, clearance rates, and potential sites of toxicity after systemic exposure.
VxP also performs standard assays, custom drug metabolism research, and IND-enabling studies to provide a number of drug/drug interaction assessments, including metabolic stability, protein binding, and metabolic profiling. Our specifically tailored, individual study designs enable our clients to quickly meet their product development goals.
Our state-of-the-art labs are staffed by some of the best trained and most experienced subject matter experts in the field.