VxP Pharma can develop methods and techniques specific to your lead candidate, and that are capable of assessing multiple models of inflammation at the membrane, cell, and whole animal levels.
We offer multiple in-vivo, ex-vivo, and in-vitro models for identification and confirmation of anti–inflammatory potential/response in NCEs and formulations.
- Acute Inflammation Models
- Carrageenan Induced
- Xylene Induced
- LPS Induced
- Chronic Inflammation Models
- MIA Induced OA
- Collagen Induced RA
- DSS / TNBS / Induced Colitis
- Oxazolone / DNFB Induced DTH Inflammation
At VxP Pharma, a complete range of pharmacology services are available to support animal models, pre-clinical studies and/or clinical trials. Our exceptional team of scientists including toxicologists, pathologists, veterinary surgeons, regulatory specialists, and support personnel have designed and performed pharmacological testing on numerous individual study designs enabling our clients to quickly meet their product development goals. We can customize our in-vivo laboratory services to meet your unique objectives in a variety of different animal models, to provide efficacy, pharmacokinetic, or toxicity data.
Inflammation Models & Screening Services
- Dendritic cell based ex vivo models
- Immune cells based model
- Target based screens for arthritis
- Target based screens for gout
- Target based screens for IBD
- Target based screens for respiratory inflammation
At VxP Pharma, we understand your needs and have the extensive experience working with the FDA, USDA, and EPA required to make your animal research projects a success. Specifically tailored, individual study designs enable our clients to meet their product development goals and facilitate world-wide regulatory approval. Our individualized approach to each study allows us to revise and shift directions based on your changing needs.
Our state-of-the-art labs are staffed by some of the best trained and most experienced subject matter experts in the field.