Pharmaceutical Toxicology

At VxP Pharma, a complete range of Pharmacokinetic (PK) and Toxicokinetic (TK) services are available to support multiple animal models, and/or pre-clinical studies.

Our toxicology team can provide PK/TK expertise with both large and small molecule drug candidates targeting a wide range of therapeutic areas.  Specialized laboratory services are also available to meet your development needs for specific bioanalytical/TK research or safety studies.  With multiple bioanalytical labs and qualified toxicologists, we can support all stages of the drug development process in accordance with current Good Lab Practice (GLP) guidelines.

PK/TK Services

• Compartmental and non-compartmental TK analysis
• Integration of TK and immunogenicity data
• Dose escalation and dose proportionality assessments
• Drug – drug interaction kinetics
• Repeat dose and assessment of steady state kinetics and linearity
• Guidance on preclinical – clinical allometric scaling
• TK study design, protocol writing and drug disposition

VxP Pharma offers rapid and dependable (GLP and Non-GLP) toxicokinetic analyses, interpretation and TK reporting of bioanalytical data generated from preclinical toxicology and drug metabolism studies.  Our TK reports are specifically designed to meet client-specific formats, and will be comprehensively reviewed by our full service Quality Assurance Department.