Dose Range Finding (DRF)

Dose Range Finding (DRF)2013-02-04T11:03:37+00:00

At VxP Pharma, a complete range of toxicologic pathology laboratory services are available to support multiple animal models, pre-clinical studies and/or clinical trials.  Our exceptional team of scientists including toxicologists, pathologists, veterinary surgeons, regulatory specialists, and support personnel have designed and performed numerous range-finding studies.  Our specifically tailored, individual study designs enable our clients to quickly meet their product development goals.

Customized in-vivo laboratory services can provide:

  • Efficacy
  • Pharmacokinetic data
  • Toxicity data
  • Utilize different animal models

Range-finding studies are very important in helping determine the maximum tolerable dose (MTD) of a drug product. Usually 5 to 14 day repeat-dose studies are conducted using a minimum number of animals to provide preliminary identification of the target organs of toxicity as well as to select doses for more definitive studies that are intended to support the clinical trials.

At VxP Pharma, we understand your needs and have the extensive experience working with the FDA, USDA, and EPA required to make your animal research projects a success.  Specifically tailored, individual study designs enable our clients to meet their product development goals and facilitate world-wide regulatory approval.  Our individualized approach to each study allows us to revise and shift directions based on your changing needs.

Our state-of-the-art labs are staffed by some of the best trained and most experienced subject matter experts in the field.

Contact us today for a free consultation with our scientific team and discover how VxP can be a valuable resource and partner for your organization.